Subtitle
Acute Toxicities After Proton Beam Therapy Following Breast-Conserving Surgery for Breast Cancer: Multi-institutional Prospective PCG Registry Analysis. This is the report of the prospective multi-institutional Proton Collaborative Group registry study.
Subtitle
Acute Toxicities After Proton Beam Therapy Following Breast-Conserving Surgery for Breast Cancer: Multi-institutional Prospective PCG Registry Analysis. This is the report of the prospective multi-institutional Proton Collaborative Group registry study.
Proto therapy Time
April 2020
Executive summary
82 patients received PBT and their adverse events (AEs) were recorded prospectively at each institution. Median follow-up was 8.1 months. Median dose was 50.4 Gy in 28 fractions. 90% patients received a lumpectomy bed boost and 83% patients received regional nodal irradiation. Six patients (7.3%) experienced grade 3 AEs (5 with dermatitis, 5 with breast pain). Body mass index (BMI) was associated with grade 3 dermatitis (P = .015). Fifty-eight patients (70.7%) experienced grade ≥2 dermatitis.
The authors concluded that PBT including RNI after BCS is well-tolerated. Elevated BMI is associated with grade 3 dermatitis.
Top cancer treatments
Other popular content
Proton Therapy Publication
December 2021
Technical insights on the treatment of GI cancers.
Proton Therapy Publication
October 2021
Impact of lymphopenia on the clinical outcomes of esophageal cancer patients
Proton Therapy Publication
October 2021
Acute Hematological Outcomes after Proton and Photon Beam Craniospinal Irradiation in Pediatric Brain Tumors
Proton Therapy Publication
October 2021
Acute Hematological Outcomes in Pediatric Brain Tumors
Proton Therapy Publication
October 2021
Comparison of hypothyroidism and adrenal insufficiency in children with medulloblastoma
Proton Therapy Publication
September 2021
Scoping review of patient selection methods for proton therapy
Proton Therapy Publication
September 2021
Dosimetry, efficacy, safety, and cost-effectiveness of PT for NSCLC
Proton Therapy Publication
September 2021
Reduced diffusion in white matter after radiotherapy with photons and protons
Proton Therapy Publication
September 2021
Particle Radiotherapy for Skull Base Chondrosarcoma
Proton Therapy Publication
September 2021
Assessing concordance between patient-reported and investigator-reported CTCAE after PBT for prostate cancer.
Proton Therapy Publication
September 2021
Current status and application of proton therapy for esophageal cancer
Proton Therapy Publication
September 2021
Bicentric Treatment Outcomes following PT for Non-Myxopapillary High-Grade Spinal Cord Ependymoma in Children
Proton Therapy Publication
September 2021
Identifying individualized risk profiles for radiotherapy-induced lymphopenia
Proton Therapy Publication
September 2021
FLASH proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response
Proton Therapy Publication
August 2021
Establishing cost-effective allocation of proton therapy for patients with mediastinal Hodgkin lymphoma