Subtitle
Early and late side effects, dosimetric parameters and quality of life after proton beam therapy and IMRT for prostate cancer: a matched-pair analysis.
Subtitle
Early and late side effects, dosimetric parameters and quality of life after proton beam therapy and IMRT for prostate cancer: a matched-pair analysis.
Proto therapy Time
March 2019
Executive summary
A study by the researchers of Dresden and Heidelberg. Eighty-eight patients with localized prostate cancer treated with PBT (31) or IMRT (57) were matched using propensity score. This study reported no significant differences in GI and GU toxicities between both treatment groups except for late urinary urgency, which was significantly lower after PBT (IMRT: 25.0%, PBT: 0%, p = .047).
The change of constipation was significantly better at 3 months after PBT compared to IMRT (p = .034). This study concluded that overall QoL and the risks of early and late GU and GI toxicities were similar for conventionally fractionated IMRT and PBT.
Key content topics
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