Subtitle
Proton Beam Therapy for Locally Advanced Head and Neck Tumors: An Analysis of Dosimetric and Clinical Outcomes.
Subtitle
Proton Beam Therapy for Locally Advanced Head and Neck Tumors: An Analysis of Dosimetric and Clinical Outcomes.
Proto therapy Time
February 2022
Executive summary
42 patients with locally advanced head and neck tumors treated with PBT were retrospectively analyzed in this study. Compared to VMAT plans, PBT plans showed a significant reduction of the mean dose and max dose to OARs, with the largest reduction mean dose in the contralateral cochlea and parotid glands at 71% and 75%. With a median follow up of 27 months, this study reported the OS rate of 44.75% at 4 years and PFS of 73.28% at 2 years. The majority of patients developed CTCAE grade I dermatitis, mucositis, or both.
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