Executive summary

This study retrospectively analyzed the renal function of 30 children with abdominal neuroblastoma treated with chemotherapy, resection of primary tumor, then proton therapy. Median follow-up after PT was 35 months. Mean dose to ipsilateral and contralateral kidney was 13.9 and 5.4 Gy, respectively. No patients developed hypertension or renal dysfunction during follow-up. There was no statistically significant change in serum blood urea nitrogen and creatinine clearance between pre-PT and last follow-up. The conclusion of this study is that renal toxicity was uncommon after PT.

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