Published in the Red Journal, the study by WPE reported outcomes of PBT for 46 pediatric patients with parameningeal rhabdomyosarcoma (pRMS). Wit a median follow-up time of 2.9 years, the estimated 2-year local control (LC), metastasis-free survival (MFS), event-free survival (EFS), and overall survival (OS) were 83.8%, 87.8%, 76.9% and 88.9%. No acute or late local toxicity exceeding grade 3 was observed.

The authors concluded that PBT was effective and well feasible even in a critical cohort. Still, local relapse within the target volume of the RT remains an important issue in pRMS and new treatment strategies are needed.