Subtitle
Phase II Study of Hypofractionated Proton Beam Therapy for Hepatocellular Carcinoma.
Subtitle
Phase II Study of Hypofractionated Proton Beam Therapy for Hepatocellular Carcinoma.
Proto therapy Time
April 2020
Executive summary
Published by the NCC group in Korea, this study reported outcomes of 45 patients including 37 had recurrent and/or residual disease treated with PBT to a total dose of 70 Gy equivalent in 10 fractions. No grade ≥3 acute toxicity occurred. The median follow-up duration was 35.1 months, local progression occurred in two patients (8.7%).
The 3-year rates of LPFS and overall survival (OS) were 95.2% and 86.4%. The study concluded that hypofractionated PBT showed promising LPFS and OS.
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