Executive summary

This study from the Heidelberg group compared the results of 111 skull-base chordoma patients treated with carbon ion of 66 GyRBE and 36 patients treated with proton of 74 GyRBE. With a median follow-up of 49.3 months, this study reported no significant differences between protons and carbon ions regarding LC, OS, or overall toxicity. The 1year, 3year, and 5year LC rates were 97%, 80%, and 61% (protons) and 96%, 80%, and 65% (carbon ions), respectively. The corresponding OS rates were 100%, 92%, and 92% (protons) and 99%, 91%, and 83% (carbon ions).

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