Subtitle
Proton Beam Therapy for Histologically or Clinically Diagnosed Stage I Non-small Cell Lung Cancer (NSCLC): The First Nationwide Retrospective Study in Japan.
Subtitle
Proton Beam Therapy for Histologically or Clinically Diagnosed Stage I Non-small Cell Lung Cancer (NSCLC): The First Nationwide Retrospective Study in Japan.
Proto therapy Time
October 2019
Executive summary
Six hundred sixty-nine patients with 682 tumors with histologically or clinically diagnosed Stage I NSCLC who received passive-scattering PBT in Japan were retrospectively reviewed to analyze survivals, local control, and toxicities. This study found that the 3-year overall survival (OS) and progression-free survival (PFS) rates for all patients were 79.5% and 64.1%.
The incidence of Grade 2, 3, 4, and 5 pneumonitis was 9.8%, 1.0%, 0%, and 0.7%, respectively. The incidence of Grade ≥3 dermatitis was 0.4%. No Grade 4 or severe adverse events, other than pneumonitis, were observed. This study concluded that PBT appears to yield acceptable survival rates, with a low rate of toxicities.
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