Subtitle
Renal function in abdominal neuroblastoma patients undergoing proton radiotherapy.
This study retrospectively analyzed the renal function of 30 children with abdominal neuroblastoma treated with chemotherapy, resection of primary tumor, then proton therapy. Median follow-up after PT was 35 months. Mean dose to ipsilateral and contralateral kidney was 13.9 and 5.4 Gy, respectively. No patients developed hypertension or renal dysfunction during follow-up. There was no statistically significant change in serum blood urea nitrogen and creatinine clearance between pre-PT and last follow-up. The conclusion of this study is that renal toxicity was uncommon after PT.