Subtitle
The role of combined ion-beam radiotherapy (CIBRT) with protons and carbon ions in a multimodal treatment strategy of inoperable osteosarcoma.
Subtitle
The role of combined ion-beam radiotherapy (CIBRT) with protons and carbon ions in a multimodal treatment strategy of inoperable osteosarcoma.
Proto therapy Time
June 2021
Executive summary
This study reported the outcomes of 20 patients with primary (N=18), metastatic (N=3), or recurrent (N=2) inoperable pelvic (70%) or craniofacial (30%) osteosarcoma treated with protons up to 54 Gy (RBE) and a carbon ion boost of 18 Gy (RBE). LPFS, DPFS, PFS and OS were 73%, 74%, 60% and 75% after one year and 55%, 65% 65.3%, 45% and 68% after two years, respectively. No acute toxicities > grade III were observed. One case of secondary acute myeloid leukemia (AML) seven months after CIBRT for recurrent disease and one case of hearing loss.
Key content topics
Top cancer treatments
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