Treatment Tolerability and Toxicity of Postoperative Proton Beam Therapy for Gynecologic Malignancies: Results of the Prospective Phase 2 APROVE Trial.
05/09/2023
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Publications
This study by the Heidelberg group reported clinical outcomes of 25 patients with uterine cervical or endometrial cancer treated with postoperative PBT. Proton...
Health-related quality of life and patient-reported symptoms after postoperative proton beam radiotherapy of cervical and endometrial cancer: 2-year results of the prospective phase II APROVE-trial.
01/03/2024
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Publications
The same study as above also reported results of QoL and patient-reported outcomes. QoL status was markedly impaired at baseline but significantly (p = 0.036)...
Outcomes of Proton Beam Therapy Compared With Intensity-Modulated Radiation Therapy for Uterine Cancer.
01/03/2024
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Publications
This study reported results of patients with uterine cancer treated with PT (n=22) and IMRT (n=45). When comparing gynecologic-specific subset of PRO-CTCAE, PT...
Outcomes of Patients Treated in the UK Proton Overseas Programme: Non-central Nervous System Group.
01/03/2024
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Publications
This report presented the results of patients with non-CNS malignancies treated in the UK proton overseas program. Four hundred and ninety-five patients were...
Acute and long-term toxicity of whole pelvis proton radiation therapy for definitive or adjuvant management of gynecologic cancers.
16/05/2023
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Publications
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Toxicity
This study reported outcomes of 23 patients with gynecologic malignancies treated with PBSPRT. 12 (52.2%) patients had uterine cancer, 10 (43.5%) cervical, and...
Proton beam re-irradiation for gastrointestinal malignancies: a systematic review.
03/02/2020
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Publications
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Reirradiation
A systematic review assessing for reports of proton-beam reirradiation for recurrent or second primary GI cancers. 7 included studies reported on proton-beam re...
Proton Reirradiation: Expert Recommendations for Reducing Toxicities and Offering New Chances of Cure in Patients With Challenging Recurrence Malignancies.
05/07/2020
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Publications
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Toxicity
Reirradiation
IMPT
Published in Seminar Radiation Oncology, this review article evaluated clinical data up-to-date on proton reirradiation for local and regional recurrence. As...
FLASH Investigations Using Protons: Design of Delivery System, Preclinical Setup and Confirmation of FLASH Effect with Protons in AnimalSystems.
01/12/2020
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Publications
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FLASH Therapy
Extremely high-dose-rate irradiation, referred to as FLASH, has been shown to be less damaging to normal tissues than the same dose administrated at...
PBT reirradiation for breast cancer: Multi-institutional prospective PCG registry analysis.
07/07/2019
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Publications
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Reirradiation
This study analyzed 50 patients received PBT reRT for breast cancer in the prospective Proton Collaborative Group (PCG) registry. Median reRT dose was 55.1 Gy...
IMPT - The future of IMRT for head and neck cancer.
01/01/2019
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Publications
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IMRT
Dosimetry
Imaging System
Reirradiation
A review article looked at the development of RT advances. There is a growing awareness of the potential clinical benefits of proton therapy over IMRT in the...
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