FLASH Radiotherapy Using Single-Energy Proton PBS Transmission Beams for Hypofractionation Liver Cancer: Dose and Dose Rate Quantification.
07/12/2021
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Publications
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FLASH Therapy
Hypofractionation
Another study by the group from New York Proton Center (ProBeam) assessed the feasibility of FLASH RT using single-energy transmission PBS plans of 4.5 Gy × 15...
Advanced pencil beam scanning Bragg peak FLASH-RT delivery technique can enhance lung cancer planning treatment outcomes compared to conventional multiple-energy proton PBS techniques.
13/09/2022
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Publications
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Dosimetry
Pencil Beam Scanning - PBS
FLASH Therapy
Published in the Green Journal, this study by the group of New York Proton Center compared the dosimetric quality between an PBS Bragg peak FLASH and...
Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial.
15/11/2022
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Publications
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FLASH Therapy
Published in JAMA, this is the results of the FAST-01 proton FLASH trial. This trial was set to test the clinical workflow feasibility, treatment related...
FLASH Radiotherapy: Current Knowledge and Future Insights Using Proton-Beam Therapy.
29/04/2024
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Publications
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Proton therapy center
FLASH Therapy
A review summarized FLASH radiotherapy research conducted to date and the current theories explaining the FLASH effect, with an emphasis on the future potential...
Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer.
06/05/2024
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Publications
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FLASH Therapy
Reirradiation
Toxicity
Survival
Published by the Upenn group, this study reported reduced xerostomia with FLASH proton compared to standard proton therapy in mice. The head and neck area of...
FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?
06/05/2024
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Publications
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FLASH Therapy
Dosimetry
Toxicity
A review article by the Upenn group summarized the preclinical and clinical evidence for the FLASH effect and discussed the potential clinical significance for...
FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach.
06/05/2024
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Publications
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FLASH Therapy
This is a trial protocol of FAST-02. This trial includes 10 patients with 1-3 painful bone metastases in the thorax, excluding bone metastases in the spine...
The current status of FLASH particle therapy: a systematic review.
16/06/2023
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Publications
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FLASH Therapy
Dosimetry
This comprehensive review summarized literatures of electron-FLASH, in vitro and in vivo studies of proton- and carbon-FLASH therapy, and the first human study...
Proton FLASH Radiation Therapy and Immune Infiltration: Evaluation in an Orthotopic Glioma Rat Model.
16/07/2023
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Publications
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FLASH Therapy
This study reported the potential immune response generated by proton-FLASH using a single dose 25 Gy at a dose rate of (257 ± 2 Gy/s) in an orthotopic glioma...
This study reported that proton-FLASH (>60 Gy/s) was more effective in reducing tumor burden and decreasing tumor cell proliferation compared conventional...
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