A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose.
16/03/2023
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Publications
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Dosimetry
Hypofractionation
Toxicity
Fifty patients were treated with PT using two different regimens following lumpectomy. 14 patients received IMPT to a total dose of 50 Gy in 25 fractions...
Radiation-induced skin and heart toxicity in patients with breast cancer treated with adjuvant proton radiotherapy: a comparison with photon radiotherapy.
16/10/2023
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Publications
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Dosimetry
Toxicity
The active and inactive (pro-BNP and NT-proBNP) forms of BNP are classically used as biomarkers for diagnosing and monitoring acute and chronic heart failure...
A phase II trial of hypofractionated high-dose proton beam therapy for unresectable liver metastases.
16/11/2022
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Publications
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Dosimetry
Toxicity
This study analyzed 46 patients with 49 liver metastases treated by PBT to a total dose of 60 GyRBE in 5 fractions (BED 132 GyE) or 70 GyRBE in 10 (BED 119 GyE)...
Proton Therapy in the Management of Pancreatic Cancer.
16/06/2022
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Publications
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Dosimetry
Reirradiation
Proton Reirradiation
Although proton treatment plans often showed advantages over photon plans in reducing dose to OARs, the clinical implications were yet to be proven. The key...
Dose-escalated proton therapy with elective nodal irradiation and concomitant chemotherapy for unresectable, borderline resectable, or medically inoperable pancreatic cancer: a phase II trial.
16/06/2022
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Publications
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Dosimetry
Reirradiation
Fifteen patients received proton therapy delivered 40.5 GyRBE in 18 fractions to the gross disease and elective nodal volumes followed by 22.5 GyRBE as a 10...
Identifying Individualized Risk Profiles for Radiotherapy-Induced Lymphopenia Among Patients With Esophageal Cancer Using Machine Learning.
16/09/2021
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Publications
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Dosimetry
This study analyzed the retrospective data of 746 patients with esophageal cancer treated with photons (n = 500) and protons (n = 246) to determine the...
Proton beam therapy in rectal cancer: A systematic review and meta-analysis.
16/09/2021
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Publications
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IMRT
Dosimetry
This review article examined eight original studies with a total of 127 patients. There was significantly less irradiated small bowel with PBT compared to 3DCRT...
Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.
16/06/2022
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Publications
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IMRT
IMPT
Dosimetry
This study compared hematologic toxicity in 41 anal cancer patients treated with IMPT (n=14) or IMRT (n=27). This study found all pelvic bone marrow dose...
The current status of FLASH particle therapy: a systematic review.
16/06/2023
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Publications
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FLASH Therapy
Dosimetry
This comprehensive review summarized literatures of electron-FLASH, in vitro and in vivo studies of proton- and carbon-FLASH therapy, and the first human study...
This study reported that proton-FLASH (>60 Gy/s) was more effective in reducing tumor burden and decreasing tumor cell proliferation compared conventional...
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