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Top cancer treatments

Proton therapy reduces the effective dose to immune cells in breast cancer patients.

29/10/2024
/ Publications

The effective dose to circulating immune cells (EDIC) is associated with survival. This study from Institut Curie compared VMAT and IMPT in EDIC in patients...

Recent update of proton beam therapy for hepatocellular carcinoma: A systematic review and meta-analysis.

29/10/2024
/ Publications

This meta-analysis included 22 original studies involving 1858 HCC patients who received PBT to a total dose ranged from 55 GyE to 76 GyE. The median proportion...

Proton beam therapy and dentofacial development in paediatric cancer patients: A scoping review.

29/10/2024
/ Publications

This review focused on the impact of PBT on dentofacial development in pediatric patients treated for cancer in the head and neck region. This review included...

Clinical practice in European centres treating paediatric posterior fossa tumours with pencil beam scanning proton therapy.

29/10/2024
/ Publications

Published in the Green Journal, this survey study sent to 19 European PT centers revealed wide variations in planning approach and consequently dose to organs...

Particle arc therapy: Status and potential.

29/10/2024
/ Publications
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ARC therapy

This comprehensive review provides perspectives from the European Society for Radiotherapy and Oncology (ESTRO) 2022 physics workshop on particle arc therapy...

Secondary cancer risk in six anatomical sites when using PAT, IMPT, and VMAT/IMRT radiotherapy.

29/10/2024
/ Publications
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ARC therapy

With dosimetric data from 90 treatment plans of six anatomical sites, five patients per site and radiation delivered by IMPT, proton arc therapy (PAT) and VMAT...

Initial experience and patient tolerance of proton stereotactic body radiotherapy.

29/10/2024
/ Publications
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Hypofractionation

This study reported treatment outcomes of 52 patients (62 lesions) treated with proton SBRT. Fractionation varied by indication and site with a median of 5...

Quantifying dose uncertainties resulting from cardiorespiratory motion in intensity-modulated proton therapy for cardiac stereotactic body radiotherapy.

29/10/2024
/ Publications
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Hypofractionation
Motion Management

This study from China investigated dose uncertainties induced by cardiorespiratory motion in proton therapy for arrhythmia. Twelve patients with refractory...

Comparison of clinical outcome between surgical treatment and particle beam therapy for pelvic bone sarcomas: A retrospective multicenter study in Japan.

29/10/2024
/ Publications

This study from Japan reported outcomes of 116 patients with pelvic bone sarcoma treated by surgery (n=57) and particle beam (n=59, 55 carbon ion, 4 proton)...

Impact of proton versus photon adjuvant radiotherapy on overall survival in the management of skull base and spinal chordomas: a National Cancer Database analysis.

29/10/2024
/ Publications

This study reported treatment outcomes of proton or photon adjuvant therapy for chordomas of the skull base and spine. Data of 424 patients from the National...