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Long-term Outcomes from Proton Therapy for Sinonasal Cancers

08/06/2021
/ Publications
/
Sinonasal
Passive scattering
Hypofractionation
Chemotherapy
Head and neck
Necrosis
Clinical Outcomes
Overall Survival

A study by the Jacksonville group reported clinical outcomes of 143 patients with nonmetastatic sinonasal cancers treated with primary (18%; n = 26) or adjuvant...

Proton Therapy for Major Salivary Gland Cancer: Clinical Outcomes

08/06/2021
/ Publications
/
Salivary Gland Cancer
Clinical Outcomes
PBT
Head and neck
Mucositis
Toxicity

A study by the MD Anderson group reported clinical outcomes of 72 patients with major salivary gland cancers (SGCs) treated by PBT. Sixty-three patients (88%)...

Oncologic Outcomes for Head and Neck Skin Malignancies Treated with Protons

08/06/2021
/ Publications
/
Head and neck
Oncology
Clinical Outcomes
Inoperable
Skin malignancies
IMPT

Radiation therapy (RT) is the standard treatment for patients with inoperable skin malignancies of the head and neck region (H&N), and as adjuvant treatment...

Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis

08/07/2021
/ Publications
/
NSCLC
Clinical Outcomes
Thoracic
Chemotherapy
IMRT

This study retrospectively reviewed 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy. 25 patients (11.4%) underwent PBSPT...

Clinical Outcomes of Patients With Unresectable Cholangiocarcinoma Treated With Proton Beam Therapy.

11/11/2019
/ Publications
/
Liver
Toxicity
Gastrointestinal
PBT
Overall Survival
Chemotherapy
Clinical Outcomes

This study from Taiwan retrospectively examined 30 patients with unresectable CC who were treated with PBT to a total dose of 72.6 GyRBE. The 1-year local...

Particle therapy in Europe. A review article looked at the status of clinical utilization of particle therapy such as protons or heavier ions in Europe.

03/04/2020
/ Publications
/
Particle Therapy
Clinical Outcomes
Clinical Trial
Methodology and Clinical Studies

From the aspects of clinical experience and current indications, randomized clinical trials and new evidence-based methodologies to the prospective clinical...

Non-homologous end joining is more important than proton linear energy transfer in dictating cell death.

07/08/2019
/ Publications
/
Dosimetry
Methodology and Clinical Studies
Clinical Outcomes

Published in the Red Journal, this study tried to identify biological factors that may yield a therapeutic advantage of proton therapy versus photon therapy...

Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma (B/P-RMS).

07/08/2019
/ Publications
/
Pediatric
Prostate
PBT
Clinical Outcomes
User Experience
Toxicity
Gastrointestinal

This study reported outcomes of 19 patients of B/P-RMS treated with PBT. With a median follow-up of 66.2 months, 5-year overall survival (OS) and progression...

Protons versus Photons for Unresectable Hepatocellular Carcinoma: Liver Decompensation and Overall Survival.

07/01/2019
/ Publications
/
Liver
Hepatocellular carcinoma
Gastrointestinal
Clinical Outcomes

Published in the Red Journal, this single-institution retrospective study compared clinical outcomes of proton versus photon ablative radiation therapy in...

Toxicity and Survival After IMPT Versus Passive Scattering PT for NSCLC.

10/10/2020
/ Publications
/
Lung
Clinical Outcomes
Toxicity
NSCLC
IMPT
Thoracic
Passive scattering

This MD Anderson study compared toxicity profiles and clinical outcomes after IMPT versus PSPT for 139 patients with locally advanced NSCLC. Compared to the...