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Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer

08/06/2021
/ Publications
/
Thyroid
Head and neck
Esophagus
IMPT

This study reported outcomes of 14 patients with recurrent, radioactive iodine (RAI) refractory differentiated thyroid cancer (DTC) treated with IMPT. At 8...

Therapeutic results of proton beam therapy with concurrent chemotherapy for cT1 esophageal cancer and salvage endoscopic therapy for local recurrence.

01/01/2020
/ Publications
/
Esophagus
Gastrointestinal
Chemotherapy
Overall Survival

This study from Japan reported the efficacy of 44 clinical T1 esophageal cancer patients treated with concurrent chemo-proton therapy (CCPT). 43 patients (98%)...

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer.

03/03/2020
/ Publications
/
Gastrointestinal
Esophagus
IMRT
IMPT
PBT
Passive scattering

Published in JCO (Journal of Clinical Oncology), this randomized trial compared total toxicity burden (TTB) and progression-free survival (PFS) between PBT and...

The emerging role of proton therapy for esophagus cancer.

03/02/2020
/ Publications
/
Gastrointestinal
Esophagus
PBT
Overall Survival

This review article discussed the emerging role of PBT for esophageal cancer, including rationale, treatment planning, early dosimetric and clinical comparisons...

Proton beam re-irradiation for gastrointestinal malignancies: a systematic review.

03/02/2020
/ Publications
/
Esophagus
Gastrointestinal
Reirradiation
Pancreas
Liver
Anal and rectal cancers

A systematic review assessing for reports of proton-beam reirradiation for recurrent or second primary GI cancers. 7 included studies reported on proton-beam re...

Scanning Beam Proton Therapy (SPT) Versus Photon IMRT for Stage III Lung Cancer: Comparison of Dosimetry, Toxicity, and Outcomes.

05/03/2020
/ Publications
/
Thoracic
Phase III
IMRT
Lung
Esophagus

This study reviewed dosimetric data and clinical outcomes of 64 stage III lung cancer patients treated with SPT (34) + IMRT (30). Mean dose to lung, heart, and...

Proton Beam Therapy Is a Safe and Effective Treatment in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESCC).

05/06/2020
/ Publications
/
Esophagus
PBT
Toxicity
Gastrointestinal
Inoperable
PBT
Overall Survival

This study from Japan reported results of 54 esophageal cancer patients who are over 75 years old treated with PBT. 38 inoperable patients (70.4%) and 16...

Incidence and Onset of Severe Cardiac Events After Radiotherapy for Esophageal Cancer.

26/06/2020
/ Publications
/
Esophagus
Severe Cardiac Events
Gastrointestinal
Overall Survival

The relatively higher cardiac dose exposure for esophageal cancer (EC) may result in the earlier onset of cardiac diseases. This MD Anderson study analyzed 479...

Proton beam radiotherapy for esophagus cancer: state of the art

10/11/2020
/ Publications
/
Esophagus
Gastrointestinal
Chemotherapy
Phase II

The majority of esophageal cancer patients are diagnosed with locoregionally confined disease, which is often amenable to curative intent therapy...

Proton therapy for thoracic malignancies: a review of oncologic outcomes

01/01/2021
/ Publications
/
Lung
Thoracic
Esophagus
Malignancies
Lymphoma

This review examined PBT physical properties, treatment techniques including the recent advances in planning and delivery, and clinical outcomes for each of the...

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