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Pediatric proton therapy

08/09/2019
/ Publications
/
Pediatric
PBT
Dosimetry
CNS
Secondary cancer risk
Paraspinal

A review article that emphasizes proton beam therapy is an important therapeutic component in multidisciplinary management in pediatric oncology because of...

Neurocognitive function and quality of life after proton beam therapy for brain tumour patients.

01/01/2020
/ Publications
/
CNS
Quality of life
PBT
Brain and CNS

Published in the Green Journal, this multicenter study reported 62 brain tumor adult patients neurocognitive function after PBT. For two years of followup time...

Proton beam therapy utilization in adults with primary brain tumors in the United States.

03/03/2020
/ Publications
/
CNS
Brain
Brain and CNS
Glioma
Medulloblastoma
Malignancies

Based on the National Cancer Database, a total of 1,296 patients received PBT from 2004 and 2015 for treatment of their primary brain tumor. High-grade glioma...

Late contrast enhancing brain lesions in proton treated low-grade glioma patients: clinical evidence for increased periventricular sensitivity and variable RBE.

03/03/2020
/ Publications
/
CNS
Glioma
Brain and CNS

Late radiation-induced contrast enhancing brain lesions (CEBL) on MR images after proton therapy of brain tumors have been observed to occur frequently in...

Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons.

05/05/2020
/ Publications
/
CNS
Lymphocyte
Proton vs Photon Therapy
Brain and CNS
Glioblastoma

This is a randomized phase II trial compared the radiation-induced grade 3+ lymphopenia (G3+L), which was defined as an absolute lymphocyte count (ALC) nadir of...

Lower doses to hippocampi and other brain structures for skull-base meningiomas with IMPT compared to photon therapy.

07/09/2019
/ Publications
/
CNS
Hippocampi
skull base
Brain and CNS
IMPT
VMAT

This study systematically compared intensity modulated proton therapy (IMPT), non-coplanar volumetric modulated arc therapy (VMAT) and intensity modulated...

Are further studies needed to justify the use of proton therapy for paediatric cancers of the central nervous system?

03/01/2019
/ Publications
/
Pediatric
CNS
Brain and CNS

A review article published in the Green Journal. Having analyzed the available data of PBT for paediatric cancers of the central nervous system (CNS), this...

Proton vs. Photon Radiation Therapy for Primary Gliomas

11/11/2018
/ Publications
/
CNS
Brain and CNS
Glioma
PBT

This is the first study that compares the outcomes of patients treated with photon based radiotherapy vs. proton based radiotherapy for patients with gliomas...

IMPT decreases dose to organs at risk in low-grade glioma patients

11/11/2018
/ Publications
/
CNS
Brain and CNS
Glioma
IMRT
VMAT
IMPT

Patients with low-grade glioma (LGG) have a prolonged survival expectancy, therefore long-term side effects caused by radiotherapy is a concern. This...

National practice patterns of proton vs photon therapy in the treatment of adult patients with primary brain tumors in the US.

08/10/2018
/ Publications
/
CNS
Brain and CNS

With National Cancer Database, 73,073 adult patients with primary brain tumors treated with radiation were analyzed (n = 72,635 [99.4%] photon therapy, n = 438...

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