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Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis

08/07/2021
/ Publications
/
Chemotherapy
IMRT

This study retrospectively reviewed 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy. 25 patients (11.4%) underwent PBSPT...

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer.

03/03/2020
/ Publications
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IMRT
IMPT

Published in JCO (Journal of Clinical Oncology), this randomized trial compared total toxicity burden (TTB) and progression-free survival (PFS) between PBT and...

Scanning Beam Proton Therapy (SPT) Versus Photon IMRT for Stage III Lung Cancer: Comparison of Dosimetry, Toxicity, and Outcomes.

05/03/2020
/ Publications
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IMRT

This study reviewed dosimetric data and clinical outcomes of 64 stage III lung cancer patients treated with SPT (34) + IMRT (30). Mean dose to lung, heart, and...

Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk.

10/10/2020
/ Publications
/
IMRT
Secondary cancer

This study estimated secondary cancer risks for 23 mediastinal lymphoma patients treated with PBT in comparison with helical photon IMRT re-plans. PBT was...

Current and emerging radiotherapy strategies for pancreatic adenocarcinoma.

08/08/2018
/ Publications
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IMRT

A review article by MD Anderson examined the available outcome data of IMRT, SBRT and proton and carbon ion therapy for locally advanced pancreatic cancer, and...

Advanced radiation techniques for locally advanced NSCLC: IMRT and proton therapy.

08/08/2018
/ Publications
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IMPT
IMRT

This review article examined clinical outcomes data of IMRT and PBT for locally advanced NSCLC. This review pointed out that PBT is not considered the standard...

Cost effectiveness of prostate cancer radiotherapy.

08/06/2018
/ Publications
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IMRT
Hypofractionation

This review article by Konski A, examined the data of cost-effectiveness analyses of various radiotherapy modalities including 3DCRT, IMRT, hypofractionated RT...

Lymphocyte-Sparing Effect of Proton Therapy in Patients with Esophageal Cancer Treated with Definitive Chemoradiation.

08/08/2018
/ Publications
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IMRT
Chemotherapy

This MD Anderson study compared IMRT and PBT chemoradiation for esophageal cancer. Patients who had IMRT and PBT matched by propensity score (n = 220) were not...

NTCP Models for Severe Radiation Induced Dermatitis After IMRT or PT for Thoracic Cancer Patients.

04/03/2020
/ Publications
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IMRT

In order to analyze the incidence of acute radiation induced dermatitis (RD) and develop normal tissue complication probability (NTCP) models for severe RD in...

High-dose Intensity-modulated proton therapy versus Standard-dose Intensity-modulated RadIation therapy for esophageal squamous cell carcinoma (HI-SIRI): study protocol for a randomized controlled clinical trial.

15/11/2022
/ Publications
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IMPT
IMRT

This is a study protocol details a randomized trial taking place in Thailand with multiple centers comparing IMPT and IMRT for stage II–IVA squamous thoracic...