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Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis

08/07/2021
/ Publications
/
NSCLC
Clinical Outcomes
Thoracic
Chemotherapy
IMRT

This study retrospectively reviewed 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy. 25 patients (11.4%) underwent PBSPT...

Treatment outcomes of passive scattering proton beam therapy for stage I non-small cell lung cancer

08/08/2021
/ Publications
/
NSCLC
Hypofractionation
Passive scattering
Thoracic
Toxicity

A study by the NCC, Korea group. This study retrospectively analyzed 42 patients with stage I NSCLC treated with protos to an initial dose of 60 CGE in 4...

Proton therapy for non-small cell lung cancer: the road ahead.

11/09/2019
/ Publications
/
Breast
Thoracic
NSCLC
Phase II

This latest review article examined the up-to-date clinical data of PBT for both early stage and locally advanced stage NSCLC. In particular, this review...

Combining Immunotherapy with Radiation Therapy in Non-Small Cell Lung Cancer.

02/03/2020
/ Publications
/
Lung
Immunotherapy
Radiotherapy
Thoracic
NSCLC

As immunotherapy, especially the immune checkpoint inhibitors have recently been demonstrated to improve survival in metastatic and locally advanced non-small...

Image-Guided Hypofractionated Proton Therapy in Early-Stage Non-Small Cell Lung Cancer: A Phase 2 Study.

10/11/2020
/ Publications
/
Lung
Thoracic
Hypofractionation
Overall Survival
NSCLC

22 patients with T1 to T2 N0M0 NSCLC received image-guided hypofractionated PBT to a total dose 48 GyRBE in 4 fractions for peripheral lesions and 60 GyRBE in...

Proton Beam Therapy for Histologically or Clinically Diagnosed Stage I Non-small Cell Lung Cancer (NSCLC): The First Nationwide Retrospective Study in Japan.

07/10/2019
/ Publications
/
Lung
NSCLC
Thoracic
Dermatitis

Six hundred sixty-nine patients with 682 tumors with histologically or clinically diagnosed Stage I NSCLC who received passive-scattering PBT in Japan were...

Quantification of global lung inflammation using volumetric 18F-FDG PET/CT parameters in locally advanced NSCLC patients treated with concurrent chemoradiotherapy

03/06/2019
/ Publications
/
Lung
Thoracic
NSCLC

This study evaluated pre-treatment and post-treatment F-FDG PET/CT of 18 locally advanced NSCLC patients treated with definitive photon or proton RT. In nine...

Clinical outcomes after IMPT with concurrent chemotherapy for inoperable NSCLC.

03/04/2019
/ Publications
/
Lung
Thoracic
Inoperable
NSCLC
Chemotherapy
Dermatitis

Published in the Green Journal, this study by MD Anderson reported disease control, survival, and toxicity in patients with advanced inoperable non-small cell...

Toxicity and Survival After IMPT Versus Passive Scattering PT for NSCLC.

10/10/2020
/ Publications
/
Lung
Clinical Outcomes
Toxicity
NSCLC
IMPT
Thoracic
Passive scattering

This MD Anderson study compared toxicity profiles and clinical outcomes after IMPT versus PSPT for 139 patients with locally advanced NSCLC. Compared to the...

Impact of unfavorable factors on outcomes among inoperable stage II-IV NSCLC patients treated with PT.

01/01/2019
/ Publications
/
Lung
Thoracic
Inoperable
NSCLC
Clinical Outcomes

A study by the Jacksonville group. 90 consecutive patients with unresectable stage II-IV (oligometastatic) NSCLC were treated with PT. Unfavorable factors...