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Proton Therapy for Head and Neck Cancer: A 12-Year, Single-Institution Experience A

08/06/2021
/ Publications
/
Head and neck
Reirradiation
Oropharyngeal Cancer
Paranasal sinus tumors
Overall Survival
Toxicity

A study by the MD Anderson group evaluated the outcomes of 573 patients treated at the institute. Oropharynx (33.3%; n = 191), paranasal sinus (11%; n = 63)...

A Systematic Review on Re-irradiation with Charged Particle Beam Therapy in the Management of Locally Recurrent Skull Base and Head and Neck Tumors

08/06/2021
/ Publications
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Reirradiation
Necrosis
Head and neck
skull base
Toxicity

A review examined a total of 26 original studies (15 protons, 10 carbon ions, and 1 helium/neon studies) involving a total of 1,118 patients (437 with protons...

Spot Scanning Proton Therapy for Sinonasal Malignant Tumors

08/06/2021
/ Publications
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Sinonasal
Head and neck
Toxicity
Malignancies

A study from Japan reported outcomes of 62 patients with sinonasal tumors treated with protons to 60 GyRBE in 15 fractions or 60.8 GyRBE in 16 fractions for...

Clinical Review of Proton Therapy in the Treatment of Unilateral Head and Neck Cancers

08/06/2021
/ Publications
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Head and neck
Salivary Gland Cancer
Skin malignancies
skull base
Oropharyngeal Cancer
Reirradiation
Toxicity

In select clinical scenarios of well-lateralized tumors, radiotherapy can be delivered to the primary tumor or tumor bed and the ipsilateral nodal regions. This...

Proton Therapy for Major Salivary Gland Cancer: Clinical Outcomes

08/06/2021
/ Publications
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Salivary Gland Cancer
Clinical Outcomes
PBT
Head and neck
Mucositis
Toxicity

A study by the MD Anderson group reported clinical outcomes of 72 patients with major salivary gland cancers (SGCs) treated by PBT. Sixty-three patients (88%)...

Financial Toxicity in Head and Neck Cancer Patients Treated With Proton Therapy

08/06/2021
/ Publications
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Head and neck
Toxicity

While cost-effectiveness analysis has been used to assess the value of proton therapy for head and neck cancer, it may not fully incorporate empiric comparisons...

FLASH proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response

08/09/2021
/ Publications
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Flash Irradiation
Toxicity
UPENN

A study by the UPenn group reported that FLASH proton radiotherapy (F-PRT) of the C57BL/6 murine hind leg produced fewer severe toxicities leading to death or...

Passively Scattered Proton Therapy for Nonmelanoma Skin Cancer with Clinical Perineural Invasion

08/06/2021
/ Publications
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Nonmelanoma Skin Cancer
Toxicity
Head and neck
Passive scattering

This study reviewed the outcomes of 26 patients who received definitive or postoperative proton therapy for nonmelanoma skin cancer with clinical perineural...

Treatment outcomes of passive scattering proton beam therapy for stage I non-small cell lung cancer

08/08/2021
/ Publications
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NSCLC
Hypofractionation
Passive scattering
Thoracic
Toxicity

A study by the NCC, Korea group. This study retrospectively analyzed 42 patients with stage I NSCLC treated with protos to an initial dose of 60 CGE in 4...

Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers

08/06/2021
/ Publications
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Proton Radiotherapy
Toxicity
Pediatric
Secondary cancer risk

Proton beam therapy is accepted as a preferred radiation modality in pediatric cancers to minimize the late radiation side effects. This review compared the...