Cross-modality applicability of rectal normal tissue complication probability models from photon- to proton-based radiotherapy.
01/10/2019
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Publications
/
Prostate
Genitourinary
Anal and rectal cancers
NTCP
Gastrointestinal
This study aimed to assess the applicability of photon-based NTCP models to rectum morbidity outcomes following PT for prostate cancer patients. The data of...
Incorporating NTCP into Randomized Trials of Proton Versus Photon Therapy.
11/03/2019
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Publications
/
NTCP
Lung
This study proposed and simulated a model-based methodology to incorporate heterogeneous treatment benefit of proton therapy versus photon therapy into...
Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial.
03/03/2020
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Publications
/
Lung
Model-based
Thoracic
NTCP
Published in the Green Journal, this study was to assess whether a model-based approach applied retrospectively to a completed randomized controlled trial (RCT)...
NTCP Models for Severe Radiation Induced Dermatitis After IMRT or Proton Therapy for Thoracic Cancer Patients.
30/04/2020
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Publications
/
Lung
Thoracic
NTCP
Dermatitis
Passive scattering
Lyman-Kutcher-Burman normal tissue complication probability modeling for radiation-induced esophagitis in non-small cell lung cancer patients receiving proton...
First experience with model-based selection of head and neck cancer patients for proton therapy.
01/06/2020
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Publications
/
Head and neck
Model-based
NTCP
Dysphagia
This study reported the first experience in model-based selection of HNC patients in the Netherlands. 227 patients were included in this study. 80 (35%)...
TORPEdO - Phase III Trial of IMPT Vs IMRT for Multi-toxicity Reduction in Oropharyngeal Cancer.
07/10/2019
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Publications
/
Head and neck
IMPT
Chemotherapy
Multi-toxicity Reduction
Oropharyngeal Cancer
Thoracic
Squamous cell carcinoma
IMRT
NTCP
This is the UK's first proton clinical trial. Published in the Clinical Oncology, this editorial provided the rational and the plan of the trial. It is a...
Model-Based Approach to Predict ST Toxicity Benefits With PT for Oropharyngeal Cancer.
01/01/2019
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Publications
/
Head and neck
Oropharyngeal Cancer
Model-based
UPENN
Oropharyngeal Cancer
NTCP
Dysphagia
Xerostomia
A study by UPenn and Groningen. For patients with advanced-stage oropharynx cancer treated with curative intent (PBT, n = 30; IMRT, n = 175), NTCP models were...
Strategy Identifying Which Oropharyngeal H&N Cancer Patients may Benefit the Most from Proton Radiation Therapy.
11/11/2018
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Publications
/
Head and neck
NTCP
Dysphagia
Hypothyroidism
Xerostomia
Mucositis
Oropharyngeal Cancer
Published in the Red Journal, this study detailed the model base approach for identifying patients for proton treatment. NTCP models for dysphagia, esophagitis...
Development and validation of NTCP models for acute side-effects resulting from PBT of brain tumours.
08/07/2018
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Publications
/
Brain
Brain and CNS
NTCP
Nausea
Alopecia
The German researchers from Dresden, Essen and Heidelberg together developed a NTCP model for acute side-effects including alopecia, scalp erythema, headache...
NTCP Models for Severe Radiation Induced Dermatitis After IMRT or PT for Thoracic Cancer Patients.
04/03/2020
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Publications
/
Lung
NTCP
Thoracic
Dermatitis
IMRT
Passive scattering
NSCLC
In order to analyze the incidence of acute radiation induced dermatitis (RD) and develop normal tissue complication probability (NTCP) models for severe RD in...
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