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A systematic review and meta-analysis of radiotherapy and particle beam therapy for skull base chondrosarcoma: TRP-chondrosarcoma 2024.
Based on 21 original studies, this meta-analysis reported a significant association of PT with a superior 5-year OS rate compared to three-dimensional conformal...
Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer.
Published by the Upenn group, this study reported reduced xerostomia with FLASH proton compared to standard proton therapy in mice. The head and neck area of...
Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas.
Sixty-seven patients with unresected spinal chordomas treated with PBT were evaluated. With a median follow-up of 56.2 months, 5- and 8-year OS were 83.5 % and...
Outcomes and prognostic factors of major salivary gland tumors treated with proton beam radiation therapy
This study reported clinical outcomes of 68 patients with major salivary gland tumors including the parotid gland (75.0%) and adenoid cystic carcinoma (22.1%)...
Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Nasopharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.
Seventy-seven patients with nonmetastatic NPC received IMPT (n=28) or IMRT(n=49). With a median follow-up time of 30.3 months, IMPT was associated with lower...
Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Oropharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.
Among the 292 patients with nonmetastatic oropharyngeal cancer of which 272 [93%] were HPV–positive tumors, 58 patients (20%) were treated with IMPT and 234 (80...
Clinical outcome after pencil beam scanning proton therapy and dysphagia/xerostomia NTCP calculations of proton and photon radiotherapy delivered to patients with cancer of the major salivary glands.
For the 26 patients with salivary gland tumor treated with PBSPT, at a median follow-up time of 46 months, 5 (19%), 2 (8%), 3 (12%) and 2 (8%) patients...