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Top cancer treatments

Show & Tell #1: Head & Neck

19/11/2020
/ User Meeting
/
Head and neck
IMPT
UPENN
Model-based

Dr Alexander Lin, Medical Director at Penn Medicine's Roberts Proton Therapy Center...

Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer

08/06/2021
/ Publications
/
Thyroid
Head and neck
Esophagus
IMPT

This study reported outcomes of 14 patients with recurrent, radioactive iodine (RAI) refractory differentiated thyroid cancer (DTC) treated with IMPT. At 8...

Work Outcomes after Intensity-Modulated Proton Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for Oropharyngeal Cancer

08/06/2021
/ Publications
/
IMPT
Oropharyngeal Cancer
Chemotherapy
Squamous cell carcinoma
Head and neck

This study compared work outcomes in patients with stage II-IVB squamous cell oropharyngeal cancer (OPC), randomized to intensity-modulated proton (IMPT) versus...

Activity-Based Costing of Intensity-Modulated Proton versus Photon Therapy for Oropharyngeal Cancer

08/06/2021
/ Publications
/
Oropharyngeal Cancer
IMPT
IMRT
Head and neck
Chemotherapy

This study used clinicopathologic factors to match 25 patients with OPC who received IMPT and 25 patients with OPC treated with IMRT. Process maps were created...

Intensity Modulated Proton Beam Therapy versus Volumetric Modulated Arc Therapy for Patients with Nasopharyngeal Cancer: A Propensity Score-Matched Study

08/07/2021
/ Publications
/
Nasopharynx
IMPT
VMAT
Head and neck

This study conducted a retrospective propensity score matching analysis (1:1) of 80 NPC patients treated with IMPT and VMAT. At a median follow-up time of 24.1...

Oncologic Outcomes for Head and Neck Skin Malignancies Treated with Protons

08/06/2021
/ Publications
/
Head and neck
Oncology
Clinical Outcomes
Inoperable
Skin malignancies
IMPT

Radiation therapy (RT) is the standard treatment for patients with inoperable skin malignancies of the head and neck region (H&N), and as adjuvant treatment...

Trends and variations in utilization and costs of radiotherapy for prostate cancer: A SEER medicare analysis from 2007 through 2016

08/02/2021
/ Publications
/
Prostate
Brachytherapy
Gastrointestinal
SBRT
IMPT

Based on the SEER database, this study reported that for Medicare beneficiaries with a first-time diagnosis of prostate cancer, the utilization of IMRT, proton...

Dose distribution of intensity-modulated proton therapy with and without a multi-leaf collimator for the treatment of maxillary sinus cancer: a comparative effectiveness study.

11/11/2019
/ Publications
/
Pencil beam scanning
IMPT
Sinonasal
Eye
Head and neck

Using collimation can sharpen the penumbra towards surrounding normal tissue in the low energy region of the proton beam, this study from Japan thus examined...

MRI-based IMPT planning for prostate cancer.

11/11/2019
/ Publications
/
Prostate
IMPT
Genitourinary

Published in the Green Journal, this study led by MGH aimed to quantify the clinical applicability of converted MR images as a substitute of CT for IMPT...

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer.

03/03/2020
/ Publications
/
Gastrointestinal
Esophagus
IMRT
IMPT
PBT
Passive scattering

Published in JCO (Journal of Clinical Oncology), this randomized trial compared total toxicity burden (TTB) and progression-free survival (PFS) between PBT and...