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Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer

08/06/2021
/ Publications
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IMPT

This study reported outcomes of 14 patients with recurrent, radioactive iodine (RAI) refractory differentiated thyroid cancer (DTC) treated with IMPT. At 8...

Activity-Based Costing of Intensity-Modulated Proton versus Photon Therapy for Oropharyngeal Cancer

08/06/2021
/ Publications
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IMPT
IMRT
Chemotherapy

This study used clinicopathologic factors to match 25 patients with OPC who received IMPT and 25 patients with OPC treated with IMRT. Process maps were created...

Intensity Modulated Proton Beam Therapy versus Volumetric Modulated Arc Therapy for Patients with Nasopharyngeal Cancer: A Propensity Score-Matched Study

08/07/2021
/ Publications
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IMPT
VMAT

This study conducted a retrospective propensity score matching analysis (1:1) of 80 NPC patients treated with IMPT and VMAT. At a median follow-up time of 24.1...

Oncologic Outcomes for Head and Neck Skin Malignancies Treated with Protons

08/06/2021
/ Publications
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IMPT

Radiation therapy (RT) is the standard treatment for patients with inoperable skin malignancies of the head and neck region (H&N), and as adjuvant treatment...

Trends and variations in utilization and costs of radiotherapy for prostate cancer: A SEER medicare analysis from 2007 through 2016

08/02/2021
/ Publications
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IMPT

Based on the SEER database, this study reported that for Medicare beneficiaries with a first-time diagnosis of prostate cancer, the utilization of IMRT, proton...

Dose distribution of intensity-modulated proton therapy with and without a multi-leaf collimator for the treatment of maxillary sinus cancer: a comparative effectiveness study.

11/11/2019
/ Publications
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Pencil Beam Scanning - PBS
IMPT

Using collimation can sharpen the penumbra towards surrounding normal tissue in the low energy region of the proton beam, this study from Japan thus examined...

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer.

03/03/2020
/ Publications
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IMRT
IMPT

Published in JCO (Journal of Clinical Oncology), this randomized trial compared total toxicity burden (TTB) and progression-free survival (PFS) between PBT and...

Comparative analysis of acute toxicities and patient reported outcomes between intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) for the treatment of oropharyngeal cancer.

03/03/2020
/ Publications
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IMPT
Chemotherapy
VMAT

This study compared 46 IMPT and 259 VMAT patients acute toxicities and reported that IMPT was associated with lower PEG-tube placement (p = 0.001) and less...

The Potential Role of Intensity-Modulated Proton Therapy in Hepatic Carcinoma in Mitigating the Risk of Dose De-Escalation

10/12/2020
/ Publications
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VMAT
IMPT

A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escalation due to the proximity of the target volumes to dose-limiting healthy...

TORPEdO - Phase III Trial of IMPT Vs IMRT for Multi-toxicity Reduction in Oropharyngeal Cancer.

07/10/2019
/ Publications
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IMPT
Chemotherapy
IMRT

This is the UK's first proton clinical trial. Published in the Clinical Oncology, this editorial provided the rational and the plan of the trial. It is a...