Longitudinal Assessment of Quality of Life in Nasopharyngeal Cancer Patients Treated with Intensity-Modulated Proton Therapy and Volumetric Modulated Arc Therapy at Different Time Points.
06/05/2024
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Publications
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IMPT
Quality of life
VMAT
This is a longitudinal assessment of QoL on 287 NPC patients treated with IMPT (n=41) and VMAT (n=246). Both groups exhibited improved scores of global QoL...
Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Nasopharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.
14/06/2021
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Publications
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Toxicity
Survival
IMPT
Seventy-seven patients with nonmetastatic NPC received IMPT (n=28) or IMRT(n=49). With a median follow-up time of 30.3 months, IMPT was associated with lower...
Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy.
14/06/2021
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Publications
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IMPT
IMRT
Toxicity
This review suggested that IMPT could de-intensifies treatment through dose de-escalation to normal tissues without compromising dose to the primary tumor and...
A comparison of acute toxicities and patient-reported outcomes between intensity-modulated proton therapy and volumetric-modulated arc therapy after ipsilateral radiation for head and neck cancers.
14/02/2022
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Publications
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IMPT
VMAT
Toxicity
ARC therapy
A cohort of tonsil and salivary gland cancer patients who received ipsilateral curative-intent radiotherapy delivered by IMPT or VMAT were reviewed. This study...
Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Oropharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.
14/11/2022
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Publications
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IMPT
IMRT
Toxicity
Survival
Among the 292 patients with nonmetastatic oropharyngeal cancer of which 272 [93%] were HPV–positive tumors, 58 patients (20%) were treated with IMPT and 234 (80...
Postmastectomy Intensity Modulated Proton Therapy: 5-Year Oncologic and Patient-Reported Outcomes.
16/11/2023
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Publications
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IMPT
127 patients received unilateral conventionally fractionated postmastectomy IMPT. Median follow-up was 4.1 years. Five-year LRC was 98.4% and OS was 87.9%...
Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.
16/06/2022
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Publications
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IMRT
IMPT
Dosimetry
This study compared hematologic toxicity in 41 anal cancer patients treated with IMPT (n=14) or IMRT (n=27). This study found all pelvic bone marrow dose...
Development of advanced preselection tools to reduce redundant plan comparisons in model-based selection of head and neck cancer patients for proton therapy.
16/07/2021
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Publications
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VMAT
IMPT
Using data from VMAT plans and volumetric data from delineated targets and OARs, the researchers developed the advanced preselection tools that prevented labor...
Optimal allocation of proton therapy slots in combined proton-photon radiotherapy.
16/09/2021
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Publications
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IMRT
IMPT
Using a cohort of 45 head-and-neck cancer patients for which IMRT and IMPT plans were previously created, in combination with NTCP models for xerostomia and...
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