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Top cancer treatments

Show&Tell #3: Thoracic cancers

07/10/2021
/ User Meeting
/
Lung

Dr Jing Zeng, Medical Director, and Dr Alex Egan, Senior Medical Physicist, will...

Incorporating NTCP into Randomized Trials of Proton Versus Photon Therapy.

11/03/2019
/ Publications
/
NTCP
Lung

This study proposed and simulated a model-based methodology to incorporate heterogeneous treatment benefit of proton therapy versus photon therapy into...

A population-based assessment of proton beam therapy utilization in California.

01/02/2020
/ Publications
/
PBT
Brain
Lung
Eye
Breast
Prostate

Based on data from California Cancer Registry, this study reported that of the 2,499,510 people with a cancer diagnosis during the study period, 578,632 (23%)...

Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial.

03/03/2020
/ Publications
/
Lung
Model-based
Thoracic
NTCP

Published in the Green Journal, this study was to assess whether a model-based approach applied retrospectively to a completed randomized controlled trial (RCT)...

Hypofractionated Proton Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: A Phase I Trial From the University of Florida and Proton Collaborative Group.

03/04/2020
/ Publications
/
Lung
Hypofractionation
Chemotherapy
Phase II
Thoracic
Phase III

Published in the Red Journal, this study reported the safety data from the first multicenter phase I trial investigating the use of hypofractionated proton...

NTCP Models for Severe Radiation Induced Dermatitis After IMRT or Proton Therapy for Thoracic Cancer Patients.

30/04/2020
/ Publications
/
Lung
Thoracic
NTCP
Dermatitis
Passive scattering

Lyman-Kutcher-Burman normal tissue complication probability modeling for radiation-induced esophagitis in non-small cell lung cancer patients receiving proton...

Combining Immunotherapy with Radiation Therapy in Non-Small Cell Lung Cancer.

02/03/2020
/ Publications
/
Lung
Immunotherapy
Radiotherapy
Thoracic
NSCLC

As immunotherapy, especially the immune checkpoint inhibitors have recently been demonstrated to improve survival in metastatic and locally advanced non-small...

Proton Reirradiation: Expert Recommendations for Reducing Toxicities and Offering New Chances of Cure in Patients With Challenging Recurrence Malignancies.

05/07/2020
/ Publications
/
Toxicity
Reirradiation
Head and neck
Malignancies
Lung
IMPT

Published in Seminar Radiation Oncology, this review article evaluated clinical data up-to-date on proton reirradiation for local and regional recurrence. As...

Scanning Beam Proton Therapy (SPT) Versus Photon IMRT for Stage III Lung Cancer: Comparison of Dosimetry, Toxicity, and Outcomes.

05/03/2020
/ Publications
/
Thoracic
Phase III
IMRT
Lung
Esophagus

This study reviewed dosimetric data and clinical outcomes of 64 stage III lung cancer patients treated with SPT (34) + IMRT (30). Mean dose to lung, heart, and...

Proton therapy for thoracic malignancies: a review of oncologic outcomes

01/01/2021
/ Publications
/
Lung
Thoracic
Esophagus
Malignancies
Lymphoma

This review examined PBT physical properties, treatment techniques including the recent advances in planning and delivery, and clinical outcomes for each of the...