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Top cancer treatments

Proton beam therapy for liver cancers.

03/02/2020
/ Publications
/
Dosimetry
Toxicity

A review article examined the latest utilization of PBT for hepatocellular carcinoma and cholangiocarcinoma, as well as liver metastasis. The dosimetric...

Early and late side effects, dosimetric parameters and QoL after PBT and IMRT for prostate cancer

03/03/2019
/ Publications
/
Dosimetry

A study by the researchers of Dresden and Heidelberg. Eighty-eight patients with localized prostate cancer treated with PBT (31) or IMRT (57) were matched using...

Proton Therapy for Prostate Cancer

11/09/2018
/ Publications
/
Dosimetry
Clinical Trial

A review examined the dosimetric rationale and theoretical benefit of proton radiation for prostate cancer and the current state of the clinical evidence for...

Finding Value for Protons: The Case of Prostate Cancer?

05/04/2018
/ Publications
/
Dosimetry
Quality of life

A review by UPenn examined the dosimetric data and clinical outcome reports. Clinical studies largely suggest no difference in urinary side effects or erectile...

Executive Summary of Clinical and Technical Guidelines for Esophageal Cancer Proton Beam Therapy From the Particle Therapy Co-Operative Group Thoracic and Gastrointestinal Subcommittees.

10/10/2021
/ Publications
/
Dosimetry
Reirradiation
Motion Management

 In this guideline document, the dosimetric data and clinical evidence of PBT for esophageal cancer (EC) was summarized and evaluated. The clinical outcome data...

Treating gastrointestinal malignancy with proton therapy

01/10/2016
/ White Paper
/
Toxicity
Dosimetry
Chemotherapy

The improved dosimetry with proton therapy enables greater sparing of normal tissues and...

FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?

06/05/2024
/ Publications
/
FLASH Therapy
Dosimetry
Toxicity

A review article by the Upenn group summarized the preclinical and clinical evidence for the FLASH effect and discussed the potential clinical significance for...

Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma

14/05/2021
/ Publications
/
Dosimetry

This study included148 chordoma and chondrosarcoma patients and 283 individual eyes with functional vision at baseline who received a minimum 30GyRBE to 0.1cm3...

Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas.

14/06/2022
/ Publications
/
Survival
Dosimetry

Sixty-seven patients with unresected spinal chordomas treated with PBT were evaluated. With a median follow-up of 56.2 months, 5- and 8-year OS were 83.5 % and...

A phase II trial of hypofractionated high-dose proton beam therapy for unresectable liver metastases.

16/11/2022
/ Publications
/
Dosimetry
Toxicity

This study analyzed 46 patients with 49 liver metastases treated by PBT to a total dose of 60 GyRBE in 5 fractions (BED 132 GyE) or 70 GyRBE in 10 (BED 119 GyE)...