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Proton beam therapy utilization in adults with primary brain tumors in the United States.

03/03/2020
/ Publications

Based on the National Cancer Database, a total of 1,296 patients received PBT from 2004 and 2015 for treatment of their primary brain tumor. High-grade glioma...

Late contrast enhancing brain lesions in proton treated low-grade glioma patients: clinical evidence for increased periventricular sensitivity and variable RBE.

03/03/2020
/ Publications

Late radiation-induced contrast enhancing brain lesions (CEBL) on MR images after proton therapy of brain tumors have been observed to occur frequently in...

Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons.

05/05/2020
/ Publications

This is a randomized phase II trial compared the radiation-induced grade 3+ lymphopenia (G3+L), which was defined as an absolute lymphocyte count (ALC) nadir of...

Neurocognitive impairment following PT for paediatric brain tumour

10/10/2020
/ Publications

In comparing cognitive changes after radiotherapy for pediatric brain tumors, this review reported significantly poorer cognitive outcome among patients treated...

Lower doses to hippocampi and other brain structures for skull-base meningiomas with IMPT compared to photon therapy.

07/09/2019
/ Publications
/
IMPT
VMAT

This study systematically compared intensity modulated proton therapy (IMPT), non-coplanar volumetric modulated arc therapy (VMAT) and intensity modulated...

Normal tissue complication probability models in plan evaluation of children with brain tumors referred to proton therapy.

07/07/2019
/ Publications
/
VMAT

40 patients treated with PBT were selected for VMAT re-plan. The VMAT and delivered PT plans were compared by dose/volume metrics and NTCP models related to...

The first prototype of spot-scanning proton arc treatment delivery.

03/05/2019
/ Publications
/
ARC therapy
IMPT

Published in the Green Journal, the Beaumont group reported the first prototype of spot-scanning arc treatment (SPArc) delivery on IBA Proteus®One. The brain...

Are further studies needed to justify the use of proton therapy for paediatric cancers of the central nervous system?

03/01/2019
/ Publications

A review article published in the Green Journal. Having analyzed the available data of PBT for paediatric cancers of the central nervous system (CNS), this...

Improved neuropsychological outcomes following proton therapy relative to x-ray therapy for pediatric brain tumor patients.

03/03/2019
/ Publications

This study analyzed 125 children who received radiation (XRT or PRT) and had post-treatment neuropsychological evaluation including intelligence (IQ), attention...

A prospective clinical trial of PT for chordoma and chondrosarcoma

03/05/2019
/ Publications

This study evaluated outcome of PBT for chordomas and chondrosarcomas. 20 adult patients with nonmetastatic chordomas of the skull base (n = 10), sacrum (n = 5)...

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