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Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy.

14/06/2021
/ Publications
/
IMPT
IMRT
Toxicity

This review suggested that IMPT could de-intensifies treatment through dose de-escalation to normal tissues without compromising dose to the primary tumor and...

A comparison of acute toxicities and patient-reported outcomes between intensity-modulated proton therapy and volumetric-modulated arc therapy after ipsilateral radiation for head and neck cancers.

14/02/2022
/ Publications
/
IMPT
VMAT
Toxicity
ARC therapy

A cohort of tonsil and salivary gland cancer patients who received ipsilateral curative-intent radiotherapy delivered by IMPT or VMAT were reviewed. This study...

Proton Therapy for Squamous Cell Carcinoma of the Head and Neck: Early Clinical Experience and Current Challenges.

14/05/2022
/ Publications
/
IMRT
Reirradiation

A significant reduction of toxicities, such as xerostomia, dysgeusia and feeding tube placement has been reported in studies of definitive PT for NPSCC...

Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Oropharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.

14/11/2022
/ Publications
/
IMPT
IMRT
Toxicity
Survival

Among the 292 patients with nonmetastatic oropharyngeal cancer of which 272 [93%] were HPV–positive tumors, 58 patients (20%) were treated with IMPT and 234 (80...

Toxicity with proton therapy for oral and/or oropharyngeal cancers: A scoping review.

14/08/2023
/ Publications
/
Toxicity

This review included 18 primary studies for analysis focusing on acute toxicities including dysphagia, radiation dermatitis, oral mucositis, dysgeusia and...

Advances in Proton Therapy for the Management of Head and Neck Tumors.

14/07/2023
/ Publications
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Toxicity

A review article summarized the advances of PBRT as compared to photon-based RT. Clinical evidence has demonstrated promising results of PBRT in the treatment...

Long-term outcomes of modern multidisciplinary management of sinonasal cancers: The M. D. Anderson experience.

14/07/2023
/ Publications
/
Toxicity
IMRT

This is study retrospectively analyzed 311 patients with sinonasal tumors treated with IMRT or PT. With median follow-up of 75 months, this study reported 10...

Clinical outcome after pencil beam scanning proton therapy and dysphagia/xerostomia NTCP calculations of proton and photon radiotherapy delivered to patients with cancer of the major salivary glands.

14/08/2023
/ Publications
/
Survival
Toxicity

For the 26 patients with salivary gland tumor treated with PBSPT, at a median follow-up time of 46 months, 5 (19%), 2 (8%), 3 (12%) and 2 (8%) patients...

A systematic review and meta-analysis of osteoradionecrosis following proton therapy in patients with head and neck cancer.

14/01/2024
/ Publications
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Toxicity

Osteoradionecrosis (ORN), which is a serious complication and late toxicity of radiotherapy, has been reported in proton therapy. This meta-analysis included 17...

Proton versus photon radiation therapy: A clinical review.

16/03/2023
/ Publications
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Clinical Trial

This review summarized comparative clinical outcomes between proton and photon radiotherapy. 63 interventional comparative studies were presented in this...