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Top cancer treatments

High-dose conformal proton therapy for clinical perineural invasion in cutaneous head and neck cancer.

11/12/2019
/ Publications
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Hypofractionation

Perineural invasion (PNI) is an uncommon (5%) which refers to tumor cell invasion extensive enough to cause clinically detectable deficits of the involved...

Proton radiotherapy and treatment delay in head and neck squamous cell carcinoma.

07/07/2016
/ Publications
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Survival

Based on the national cancer database, there were total of 175,088 patients with HNSCC receiving either photon or proton RT. This analysis pointed out that...

A population-based assessment of proton beam therapy utilization in California.

01/02/2020
/ Publications

Based on data from California Cancer Registry, this study reported that of the 2,499,510 people with a cancer diagnosis during the study period, 578,632 (23%)...

Minimal acute toxicity from proton beam therapy for major salivary gland cancer.

11/12/2019
/ Publications

This multicenter study reported acute toxicity outcomes of patients with major salivary gland cancers registered on the Proton Collaborative Group REG001-09...

Reduced radiation-induced toxicity by using proton therapy for the treatment of oropharyngeal cancer.

01/01/2020
/ Publications
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Model-based approach
Quality of life

Published in the British Journal of Radiology by the Groningen group, this review paper examined the outcome reports of oropharyngeal cancer patients treated...

Proton beam therapy utilization in adults with primary brain tumors in the United States.

03/03/2020
/ Publications

Based on the National Cancer Database, a total of 1,296 patients received PBT from 2004 and 2015 for treatment of their primary brain tumor. High-grade glioma...

Comparative analysis of acute toxicities and patient reported outcomes between intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) for the treatment of oropharyngeal cancer.

03/03/2020
/ Publications
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IMPT
Chemotherapy
VMAT

This study compared 46 IMPT and 259 VMAT patients acute toxicities and reported that IMPT was associated with lower PEG-tube placement (p = 0.001) and less...

Outcomes following limited-volume proton therapy for multifocal spinal myxopapillary ependymoma

10/11/2020
/ Publications
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Toxicity

A study by the Jacksonville group reported the disease control and toxicity in 12 pediatric patients with multifocal spinal myxopapillary ependymoma (MPE)...

Past, present and future of proton therapy for head and neck cancer.

05/07/2020
/ Publications

This latest review article examined the current evidence in major subsites within the head and neck to facilitate a greater understanding of the full risks and...

Proton therapy following induction chemotherapy for pediatric and adolescent nasopharyngeal carcinoma.

07/09/2019
/ Publications
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Chemotherapy
Survival

A study by the Jacksonville group. Seventeen patients with nonmetastatic nasopharyngeal carcinoma underwent double-scattered proton therapy. With the median...