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A Review of Particle Therapy for Skull Base Tumors: Modern Considerations and Future Directions

08/06/2021
/ Publications
A review on proton therapy for skull base tumors including chordoma and chondrosarcoma, pituitary adenoma and acoustic neuroma. Proton therapy for skull base...

Spot Scanning Proton Therapy for Sinonasal Malignant Tumors

08/06/2021
/ Publications
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Toxicity

A study from Japan reported outcomes of 62 patients with sinonasal tumors treated with protons to 60 GyRBE in 15 fractions or 60.8 GyRBE in 16 fractions for...

Long-term Outcomes from Proton Therapy for Sinonasal Cancers

08/06/2021
/ Publications
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Hypofractionation
Chemotherapy
Survival

A study by the Jacksonville group reported clinical outcomes of 143 patients with nonmetastatic sinonasal cancers treated with primary (18%; n = 26) or adjuvant...

Clinical Review of Proton Therapy in the Treatment of Unilateral Head and Neck Cancers

08/06/2021
/ Publications
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Reirradiation
Toxicity

In select clinical scenarios of well-lateralized tumors, radiotherapy can be delivered to the primary tumor or tumor bed and the ipsilateral nodal regions. This...

Proton Therapy for Major Salivary Gland Cancer: Clinical Outcomes

08/06/2021
/ Publications
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Toxicity

A study by the MD Anderson group reported clinical outcomes of 72 patients with major salivary gland cancers (SGCs) treated by PBT. Sixty-three patients (88%)...

The Role of Particle Therapy in Adenoid Cystic Carcinoma and Mucosal Melanoma of the Head and Neck

08/06/2021
/ Publications

Adenoid cystic carcinoma and mucosal melanoma are two radioresistant tumors and lying closely proximal to critical structures. This review article examined...

Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer

08/06/2021
/ Publications
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IMPT

This study reported outcomes of 14 patients with recurrent, radioactive iodine (RAI) refractory differentiated thyroid cancer (DTC) treated with IMPT. At 8...

Financial Toxicity in Head and Neck Cancer Patients Treated With Proton Therapy

08/06/2021
/ Publications
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Toxicity

While cost-effectiveness analysis has been used to assess the value of proton therapy for head and neck cancer, it may not fully incorporate empiric comparisons...

Activity-Based Costing of Intensity-Modulated Proton versus Photon Therapy for Oropharyngeal Cancer

08/06/2021
/ Publications
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IMPT
IMRT
Chemotherapy

This study used clinicopathologic factors to match 25 patients with OPC who received IMPT and 25 patients with OPC treated with IMRT. Process maps were created...

Intensity Modulated Proton Beam Therapy versus Volumetric Modulated Arc Therapy for Patients with Nasopharyngeal Cancer: A Propensity Score-Matched Study

08/07/2021
/ Publications
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IMPT
VMAT

This study conducted a retrospective propensity score matching analysis (1:1) of 80 NPC patients treated with IMPT and VMAT. At a median follow-up time of 24.1...