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Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis

08/07/2021
/ Publications
/
NSCLC
Clinical Outcomes
Thoracic
Chemotherapy
IMRT

This study retrospectively reviewed 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy. 25 patients (11.4%) underwent PBSPT...

Treatment outcomes of passive scattering proton beam therapy for stage I non-small cell lung cancer

08/08/2021
/ Publications
/
NSCLC
Hypofractionation
Passive scattering
Thoracic
Toxicity

A study by the NCC, Korea group. This study retrospectively analyzed 42 patients with stage I NSCLC treated with protos to an initial dose of 60 CGE in 4...

Incorporating NTCP into Randomized Trials of Proton Versus Photon Therapy.

11/03/2019
/ Publications
/
NTCP
Lung

This study proposed and simulated a model-based methodology to incorporate heterogeneous treatment benefit of proton therapy versus photon therapy into...

Proton therapy for non-small cell lung cancer: the road ahead.

11/09/2019
/ Publications
/
Breast
Thoracic
NSCLC
Phase II

This latest review article examined the up-to-date clinical data of PBT for both early stage and locally advanced stage NSCLC. In particular, this review...

Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System.

01/02/2020
/ Publications
/
Flash Proton Therapy
UPENN
Fibrosis
Flash Irradiation
Thoracic
Gastrointestinal

Published in the Red Journal by the UPenn group, this paper reported the effect of FLASH proton versus standard dose rate PRT on tumors and normal tissues in...

A population-based assessment of proton beam therapy utilization in California.

01/02/2020
/ Publications
/
PBT
Brain
Lung
Eye
Breast
Prostate

Based on data from California Cancer Registry, this study reported that of the 2,499,510 people with a cancer diagnosis during the study period, 578,632 (23%)...

Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial.

03/03/2020
/ Publications
/
Lung
Model-based
Thoracic
NTCP

Published in the Green Journal, this study was to assess whether a model-based approach applied retrospectively to a completed randomized controlled trial (RCT)...

Hypofractionated Proton Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: A Phase I Trial From the University of Florida and Proton Collaborative Group.

03/04/2020
/ Publications
/
Lung
Hypofractionation
Chemotherapy
Phase II
Thoracic
Phase III

Published in the Red Journal, this study reported the safety data from the first multicenter phase I trial investigating the use of hypofractionated proton...

NTCP Models for Severe Radiation Induced Dermatitis After IMRT or Proton Therapy for Thoracic Cancer Patients.

30/04/2020
/ Publications
/
Lung
Thoracic
NTCP
Dermatitis
Passive scattering

Lyman-Kutcher-Burman normal tissue complication probability modeling for radiation-induced esophagitis in non-small cell lung cancer patients receiving proton...

Combining Immunotherapy with Radiation Therapy in Non-Small Cell Lung Cancer.

02/03/2020
/ Publications
/
Lung
Immunotherapy
Radiotherapy
Thoracic
NSCLC

As immunotherapy, especially the immune checkpoint inhibitors have recently been demonstrated to improve survival in metastatic and locally advanced non-small...

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