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Bone Marrow Sparing by Intensity Modulated Proton Beam Therapy in Postoperative Irradiation of Gynecologic Malignancies.

30/10/2024
/ Publications

This matched-pair cohort study from the Heidelberg group evaluated IMPT for 25 patients with uterine cervical (n = 8) or endometrial cancer (n = 17), comparing...

Long Term Results of a Phase II Study of Adjuvant Proton Radiotherapy for Node-Positive Cancer of the Uterus and Cervix: Proton Radiation for Uterine/Cervical Cancer.

07/04/2025
/ Publications

Published in the Red Journal, this study from MGH reported treatment outcomes of 21 patients with node-positive uterine or cervical cancer treated with post...

Treatment Tolerability and Toxicity of Postoperative Proton Beam Therapy for Gynecologic Malignancies: Results of the Prospective Phase 2 APROVE Trial.

05/09/2023
/ Publications

This study by the Heidelberg group reported clinical outcomes of 25 patients with uterine cervical or endometrial cancer treated with postoperative PBT. Proton...

Health-related quality of life and patient-reported symptoms after postoperative proton beam radiotherapy of cervical and endometrial cancer: 2-year results of the prospective phase II APROVE-trial.

01/03/2024
/ Publications

The same study as above also reported results of QoL and patient-reported outcomes. QoL status was  markedly impaired at baseline but significantly (p = 0.036)...

Outcomes of Proton Beam Therapy Compared With Intensity-Modulated Radiation Therapy for Uterine Cancer.

01/03/2024
/ Publications

This study reported results of patients with uterine cancer treated with PT (n=22) and IMRT (n=45). When comparing gynecologic-specific subset of PRO-CTCAE, PT...

Outcomes of Patients Treated in the UK Proton Overseas Programme: Non-central Nervous System Group.

01/03/2024
/ Publications

This report presented the results of patients with non-CNS malignancies treated in the UK proton overseas program. Four hundred and ninety-five patients were...

Acute and long-term toxicity of whole pelvis proton radiation therapy for definitive or adjuvant management of gynecologic cancers.

16/05/2023
/ Publications
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Toxicity

This study reported outcomes of 23 patients with gynecologic malignancies treated with PBSPRT. 12 (52.2%) patients had uterine cancer, 10 (43.5%) cervical, and...

Comparison of clinical outcome between surgical treatment and particle beam therapy for pelvic bone sarcomas: A retrospective multicenter study in Japan.

29/10/2024
/ Publications

This study from Japan reported outcomes of 116 patients with pelvic bone sarcoma treated by surgery (n=57) and particle beam (n=59, 55 carbon ion, 4 proton)...

Impact of proton versus photon adjuvant radiotherapy on overall survival in the management of skull base and spinal chordomas: a National Cancer Database analysis.

29/10/2024
/ Publications

This study reported treatment outcomes of proton or photon adjuvant therapy for chordomas of the skull base and spine. Data of 424 patients from the National...

Systematic Review and Meta-Analysis of Particle Beam Therapy versus Photon Radiotherapy for Skull Base Chordoma: TRP-Chordoma 2024.

29/10/2024
/ Publications

This analysis from Japan based on 30 selected studies reported higher 5-year progression-free survival with particle beam therapy compared to photon RT for...