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Bone Marrow Sparing by Intensity Modulated Proton Beam Therapy in Postoperative Irradiation of Gynecologic Malignancies.

30/10/2024
/ Publications

This matched-pair cohort study from the Heidelberg group evaluated IMPT for 25 patients with uterine cervical (n = 8) or endometrial cancer (n = 17), comparing...

Long Term Results of a Phase II Study of Adjuvant Proton Radiotherapy for Node-Positive Cancer of the Uterus and Cervix: Proton Radiation for Uterine/Cervical Cancer.

07/04/2025
/ Publications

Published in the Red Journal, this study from MGH reported treatment outcomes of 21 patients with node-positive uterine or cervical cancer treated with post...

Treatment Tolerability and Toxicity of Postoperative Proton Beam Therapy for Gynecologic Malignancies: Results of the Prospective Phase 2 APROVE Trial.

05/09/2023
/ Publications

This study by the Heidelberg group reported clinical outcomes of 25 patients with uterine cervical or endometrial cancer treated with postoperative PBT. Proton...

Health-related quality of life and patient-reported symptoms after postoperative proton beam radiotherapy of cervical and endometrial cancer: 2-year results of the prospective phase II APROVE-trial.

01/03/2024
/ Publications

The same study as above also reported results of QoL and patient-reported outcomes. QoL status was  markedly impaired at baseline but significantly (p = 0.036)...

Outcomes of Proton Beam Therapy Compared With Intensity-Modulated Radiation Therapy for Uterine Cancer.

01/03/2024
/ Publications

This study reported results of patients with uterine cancer treated with PT (n=22) and IMRT (n=45). When comparing gynecologic-specific subset of PRO-CTCAE, PT...

Outcomes of Patients Treated in the UK Proton Overseas Programme: Non-central Nervous System Group.

01/03/2024
/ Publications

This report presented the results of patients with non-CNS malignancies treated in the UK proton overseas program. Four hundred and ninety-five patients were...

Acute and long-term toxicity of whole pelvis proton radiation therapy for definitive or adjuvant management of gynecologic cancers.

16/05/2023
/ Publications
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Toxicity

This study reported outcomes of 23 patients with gynecologic malignancies treated with PBSPRT. 12 (52.2%) patients had uterine cancer, 10 (43.5%) cervical, and...

Establishing cost-effective allocation of proton therapy for patients with mediastinal Hodgkin lymphoma

08/08/2021
/ Publications
/
Dosimetry
IMRT

A health-economic study by the Jacksonville group. This study utilized (1) patient-level dosimetric information for a cost-effectiveness analysis using a Markov...

Current Situation of Proton Therapy for Hodgkin Lymphoma: From Expectations to Evidence

08/07/2021
/ Publications
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Secondary cancer

Consolidative radiation therapy (RT) is of prime importance for early-stage Hodgkin lymphoma (HL) management since it significantly increases progression-free...

Proton Therapy For Lymphomas: Current State Of The Art

01/10/2019
/ Publications

A review of latest development on lymphomas management with proton therapy, including details of proton physic properties, delivery techniques of passive...