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Proton beam therapy for clival chordoma: Optimising rare cancer treatments in Australia.

06/05/2024
/ Publications
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Quality assurance

This review evaluated clinical evidence of surgery, photon-based radiotherapy and proton therapy for clival chordoma. The authors stated that contemporaneous...

FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?

06/05/2024
/ Publications
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FLASH Therapy
Dosimetry
Toxicity

A review article by the Upenn group summarized the preclinical and clinical evidence for the FLASH effect and discussed the potential clinical significance for...

Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma

14/05/2021
/ Publications
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Dosimetry

This study included148 chordoma and chondrosarcoma patients and 283 individual eyes with functional vision at baseline who received a minimum 30GyRBE to 0.1cm3...

Particle Radiotherapy for Skull Base Chondrosarcoma: A Clinical Series from Italian National Center for Oncological Hadrontherapy.

14/09/2021
/ Publications
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Toxicity

This study reported outcomes of 48 patients with skull base chondrosarcoma who underwent particle therapy (67% PT, 33% CIRT). With a median follow-up of 38...

Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas.

14/06/2022
/ Publications
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Survival
Dosimetry

Sixty-seven patients with unresected spinal chordomas treated with PBT were evaluated. With a median follow-up of 56.2 months, 5- and 8-year OS were 83.5 % and...

Proton or Carbon Ion Therapy for Skull Base Chordoma: Rationale and First Analysis of a Mono-Institutional Experience.

14/03/2023
/ Publications
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Toxicity

This study reported clinical outcomes of 44 patients treated with proton (89%) or carbon ion therapy (11%). At a median follow-up of 34.3 months, 2-, and 3-year...

The role of combined ion-beam radiotherapy (CIBRT) with protons and carbon ions in a multimodal treatment strategy of inoperable osteosarcoma.

16/06/2021
/ Publications
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Toxicity

This study reported the outcomes of 20 patients with primary (N=18), metastatic (N=3), or recurrent (N=2) inoperable pelvic (70%) or craniofacial (30%)...

Proton Therapy for Primary Bone Malignancy of the Pelvic and Lumbar Region - Data From the Prospective Registries ProReg and KiProReg.

16/02/2022
/ Publications
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Toxicity

Eighty-one patients with primary bone malignancy, including Ewing’s sarcoma (58%), chondrosarcoma (7.4%), chordoma (24.7%), osteosarcoma (7.4%), and...

The Potential and Challenges of Proton FLASH in Head and Neck Cancer Reirradiation.

05/11/2024
/ Publications
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FLASH Therapy

This review discussed the potential of proton FLASH for head and neck cancer reirradiation, highlighting the proton conformal FLASH techniques, which uses the...

The Radiosurgery Society Working Groups on GRID, LATTICE, Microbeam, and FLASH Radiotherapies: 2022 - 2023 Advancements Symposium and Subsequent Progress Made.

05/11/2024
/ Publications
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FLASH Therapy

This is a report of a symposium focusing on spatially fractionated radiotherapy (SFRT) including GRID, Lattice, Microbeam, as well as ultra-high dose rate...