Subtitle
Clinical trial of proton craniospinal irradiation for leptomeningeal metastases.
Subtitle
Clinical trial of proton craniospinal irradiation for leptomeningeal metastases.
Proto therapy Time
January 2021
Executive summary
This study reported the outcomes of 24 patients with leptomeningeal metastases (LM) treated with proton craniospinal irradiation (CSI). With the median follow-up was 11 months, two patients experienced grade 4 lymphopenia, grade 4 thrombocytopenia, and/or grade 3 fatigue. The median CNS PFS was 7 months and the median OS was 8 months. Four patients (19%) were progression-free in the CNS for more than 12 months.
Key content topics
Top cancer treatments
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