Executive summary

This study analyzed 124 patients who underwent proton therapy with gastrointestinal tract involved in the irradiated field. The study reported gastrointestinal bleeding/ulcer occurred in 4 patients (3.2%), with no death due to the bleeding/ulcer. The authors suggested that upper gastrointestinal irradiation in older children undergoing intensive chemotherapy may increase the risk of developing gastrointestinal complications. 

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