Executive summary

Published in the Green Journal, the PTCOG lymphoma subcommittee conducted a systematic review on available dosimetric studies comparing IMPT free breathing (FB) and/or deep inspiration breath hold (DIBH) with IMRT-DIBH, focusing on mean heart dose (MHD), mean lung dose (MLD), and mean breast dose (MBD). This review reported that proton with FB or DIBH was superior to IMRT-DIBH in heart, lung, breast, and integral dose, and IMPT with DIBH can further lower doses to lungs and heart. The utilization of proton therapy with DIBH may provide the best opportunity at OAR sparing in mediastinal lymphoma.

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