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Top cancer treatments

Proton Therapy in the Management of Pancreatic Cancer.

16/06/2022
/ Publications
/
Dosimetry
Reirradiation
Proton Reirradiation

Although proton treatment plans often showed advantages over photon plans in reducing dose to OARs, the clinical implications were yet to be proven. The key...

Dose-escalated proton therapy with elective nodal irradiation and concomitant chemotherapy for unresectable, borderline resectable, or medically inoperable pancreatic cancer: a phase II trial.

16/06/2022
/ Publications
/
Dosimetry
Reirradiation

Fifteen patients received proton therapy delivered 40.5 GyRBE in 18 fractions to the gross disease and elective nodal volumes followed by 22.5 GyRBE as a 10...

The Promise of Proton Beam Therapy for Oesophageal Cancer: A Systematic Review of Dosimetric and Clinical Outcomes.

16/08/2021
/ Publications
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Toxicity
Survival

Based on 32 publications, this review reported that significant benefits with PBT suggested by current literature in terms of toxicity reduction, especially in...

Identifying Individualized Risk Profiles for Radiotherapy-Induced Lymphopenia Among Patients With Esophageal Cancer Using Machine Learning.

16/09/2021
/ Publications
/
Dosimetry

This study analyzed the retrospective data of 746 patients with esophageal cancer treated with photons (n = 500) and protons (n = 246) to determine the...

The impact of lymphopenia during chemoradiotherapy using photons or protons on the clinical outcomes of esophageal cancer patients.

16/10/2021
/ Publications
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Chemotherapy

This study retrospectively review 69 patients with esophageal cancer treated with XRT (n=15) and PBT (n= 54) and concurrent chemotherapy. The study found that...

A Comparative Analysis of Photon versus Proton Beam Therapy in Neoadjuvant Concurrent Chemoradiotherapy for Intrathoracic Squamous Cell Carcinoma of the Esophagus at a Single Institute.

16/04/2022
/ Publications
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Chemotherapy

This study compared the results of 31 patients with locally advanced esophageal cancer treated with neoadjuvant chemoradiotherapy to a median total dose 41.4 Gy...

Analysis of particle therapy registries based on a unified treatment policy for esophageal cancer.

16/06/2023
/ Publications
/
Toxicity

Based on data from a registry, clinical outcomes of 174 patients were analyzed in this study. With a median follow-up period 908 days, the 3-year OS rates for...

Proton beam therapy in rectal cancer: A systematic review and meta-analysis.

16/09/2021
/ Publications
/
IMRT
Dosimetry

This review article examined eight original studies with a total of 127 patients. There was significantly less irradiated small bowel with PBT compared to 3DCRT...

Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.

16/06/2022
/ Publications
/
IMRT
IMPT
Dosimetry

This study compared hematologic toxicity in 41 anal cancer patients treated with IMPT (n=14) or IMRT (n=27). This study found all pelvic bone marrow dose...

Proton versus photon radiation therapy: A clinical review.

16/03/2023
/ Publications
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Clinical Trial

This review summarized comparative clinical outcomes between proton and photon radiotherapy. 63 interventional comparative studies were presented in this...