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Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons.

05/05/2020
/ Publications

This is a randomized phase II trial compared the radiation-induced grade 3+ lymphopenia (G3+L), which was defined as an absolute lymphocyte count (ALC) nadir of...

Roadmap: proton therapy physics and biology

02/02/2021
/ Publications
/
Dosimetry
Proton therapy center
PT101

This review presented the roadmap for proton therapy development, which included further research in the advanced dose shaping capabilities of proton therapy...

Comparing second cancer risk for multiple radiotherapy modalities in survivors of Hodgkin lymphoma

10/04/2021
/ Publications
/
Secondary cancer
VMAT

Using Excess Absolute Risk (EAR) models, this study compared the risk of secondary cancer for Hodgkin lymphoma survivors after either IMRT or PBT radiation...

Multivariate normal tissue complication probability models for rectal and bladder morbidity in prostate cancer patients treated with proton therapy

10/10/2020
/ Publications

The study included rectum and bladder DVHs, 2D rectal dose maps and relevant patient/treatment characteristics from 1151 prostate cancer cases treated with PT...

Comparative Analysis of 5-Year Clinical Outcomes and Patterns of Failure of Proton Beam Therapy (PBT) versus Intensity-Modulated Radiotherapy (IMRT) for Prostate Cancer in the Postoperative Setting

10/11/2020
/ Publications
/
IMRT

This case-matched study analyzed 260 prostate cancer patients including 65 treated with PBT and 195 IMRT. At a median follow-up of 59 months, biochemical...

Proton beam radiotherapy for esophagus cancer: state of the art

10/11/2020
/ Publications
/
Chemotherapy

The majority of esophageal cancer patients are diagnosed with locoregionally confined disease, which is often amenable to curative intent therapy...

The Potential Role of Intensity-Modulated Proton Therapy in Hepatic Carcinoma in Mitigating the Risk of Dose De-Escalation

10/12/2020
/ Publications
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VMAT
IMPT

A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escalation due to the proximity of the target volumes to dose-limiting healthy...

Efficacy and feasibility of proton beam radiotherapy using the simultaneous integrated boost technique for locally advanced pancreatic cancer

10/12/2020
/ Publications

A study by the NCC, Korea group analyzed 81 patients with locally advanced pancreatic cancer (LAPC), treated with PBT simultaneous integrated boost (SIB)...

Proton therapy for thoracic malignancies: a review of oncologic outcomes

01/01/2021
/ Publications

This review examined PBT physical properties, treatment techniques including the recent advances in planning and delivery, and clinical outcomes for each of the...

Outcomes following limited-volume proton therapy for multifocal spinal myxopapillary ependymoma

10/11/2020
/ Publications
/
Toxicity

A study by the Jacksonville group reported the disease control and toxicity in 12 pediatric patients with multifocal spinal myxopapillary ependymoma (MPE)...