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FLASH Investigations Using Protons: Design of Delivery System, Preclinical Setup and Confirmation of FLASH Effect with Protons in AnimalSystems.

01/12/2020
/ Publications
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FLASH Therapy

Extremely high-dose-rate irradiation, referred to as FLASH, has been shown to be less damaging to normal tissues than the same dose administrated at...

Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk.

10/10/2020
/ Publications
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IMRT
Secondary cancer

This study estimated secondary cancer risks for 23 mediastinal lymphoma patients treated with PBT in comparison with helical photon IMRT re-plans. PBT was...

Proton pencil beam scanning reduces secondary cancer risk in breast cancer patients with internal mammary chain involvement compared to photon radiotherapy.

01/10/2020
/ Publications
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Secondary cancer

This study compared tangential 3D-CRT and VMAT to PBS proton therapy in secondary cancer risk (SCR) for the lungs and for contralateral breast. PBS PT was...

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group.

10/11/2020
/ Publications
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Hypofractionation

This study analyzed the data of 63 patients with liver tumors treated with PBT. Hypofractionated PBT resulted in excellent local control, sparing of the...

Proton beam radiotherapy vs. radiofrequency ablation for recurrent hepatocellular carcinoma: a randomized phase trial.

01/10/2020
/ Publications
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Toxicity

This randomized study compared PBT and radiofrequency ablation (RFA) for patients with recurrent/residual HCC. The local progression free survival values of PBT...

Image-Guided Hypofractionated Proton Therapy in Early-Stage Non-Small Cell Lung Cancer: A Phase 2 Study.

10/11/2020
/ Publications
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Hypofractionation
Survival

22 patients with T1 to T2 N0M0 NSCLC received image-guided hypofractionated PBT to a total dose 48 GyRBE in 4 fractions for peripheral lesions and 60 GyRBE in...

First experience with model-based selection of head and neck cancer patients for proton therapy.

01/06/2020
/ Publications
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Model-based approach

This study reported the first experience in model-based selection of HNC patients in the Netherlands. 227 patients were included in this study. 80 (35%)...

Past, present and future of proton therapy for head and neck cancer.

05/07/2020
/ Publications

This latest review article examined the current evidence in major subsites within the head and neck to facilitate a greater understanding of the full risks and...

Neurocognitive impairment following PT for paediatric brain tumour

10/10/2020
/ Publications

In comparing cognitive changes after radiotherapy for pediatric brain tumors, this review reported significantly poorer cognitive outcome among patients treated...

Proton Accelerated Partial Breast Irradiation

09/09/2020
/ Publications

Published in the Red Journal, this MD Anderson study reported on the interim analysis of acute and late toxicities and cosmetic outcomes after proton APBI for...