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Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis.

14/07/2021
/ Publications
/
IMRT
Pencil Beam Scanning - PBS

For a cohort of 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy, 25 patients (11.4%) underwent PBSPT and 194 patients (88...

Dosimetry, Efficacy, Safety, and Cost-Effectiveness of Proton Therapy for Non-Small Cell Lung Cancer.

14/09/2021
/ Publications
/
Toxicity
IMRT

In the early-stage NSCLC setting, all of the studies had a small sample size and were single-arm without direct comparison. Proton therapy was promising for...

Prospective Study of Proton Therapy for Lung Cancer Patients with Poor Lung Function or Pulmonary Fibrosis.

15/05/2022
/ Publications
/
Toxicity

This study reported results of PBT for 54 patients of inoperable stage I to III NSCLC with poor lung functions (defined as FEV1 ≤1.0 L, or FEV1≤50% predicted or...

Outcomes of proton therapy for non-small cell lung cancer in patients with interstitial pneumonia.

16/03/2022
/ Publications
/
Toxicity

This study reported outcomes of 29 stage I to III NSCLC patients with interstitial pneumonia (IP) treated with PT. With a median follow up of 21.1 months, this...

Chemoradiation with Hypofractionated Proton Therapy in Stage II-III Non-Small Cell Lung Cancer: A Proton Collaborative Group Phase 1/2 Trial.

16/07/2022
/ Publications
/
Toxicity
Chemotherapy

This study presented outcomes of a prospective multicenter trial with an early closure. Twenty-eight patients with stage II or III unresectable NSCLC were...

Exposure of the heart in lung cancer radiation therapy: A systematic review of heart doses published during 2013 to 2020.

01/07/2022
/ Publications
/
Dosimetry
IMRT
Motion Management

Data of 140 dosimetry studies was analyzed. In the 105 non-SABR studies, the average MHD was similar between IMRT and 3DCRT (10.9 Gy versus 10.6 Gy) and lower...

Effects of lymphopenia on survival in proton therapy with chemotherapy for non-small cell lung cancer.

16/03/2023
/ Publications
/
Chemotherapy
Survival

With data of 41 patients with stage III NSCLC who received PBT of 74 GyE with concurrent chemotherapy, this study reported that bone V5-20 and lung V5-50 were...

Efficacy and safety of particle therapy for inoperable stage II-III non-small cell lung cancer: a systematic review and meta-analysis.

16/05/2023
/ Publications

This review provided systematic evidence for evaluating the efficacy and safety of particle therapy for inoperable locally advanced NSCLC. Based on 19 studies...

ASTRO Radiation Therapy Summary of the ASCO Guideline on Management of Stage III Non-Small Cell Lung Cancer.

16/06/2023
/ Publications
/
Dosimetry

Based on the ‘Management of Stage III Non-Small-Cell Lung Cancer: ASCO Guideline’, this summary document makes recommendations directly related to RT for the...

The impact of lymphopenia during chemoradiotherapy using photons or protons on the clinical outcomes of esophageal cancer patients.

16/10/2021
/ Publications
/
Chemotherapy

This study retrospectively review 69 patients with esophageal cancer treated with XRT (n=15) and PBT (n= 54) and concurrent chemotherapy. The study found that...

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