Subtitle
Initial experience with intensity modulated proton therapy for intact, clinically localized pancreas cancer: Clinical implementation, dosimetric analysis, acute treatment-related adverse events, and patient-reported outcomes.
Subtitle
Initial experience with intensity modulated proton therapy for intact, clinically localized pancreas cancer: Clinical implementation, dosimetric analysis, acute treatment-related adverse events, and patient-reported outcomes.
Proto therapy Time
April 2018
Executive summary
A Mayo Clinic study reported outcomes of IMPT for intact and clinically localized pancreatic cancer. 13 patients with localized pancreatic cancer underwent concurrent chemoradiation therapy utilizing IMPT to a dose of 50 Gy.
All patients completed treatment without radiation therapy breaks. The median weight loss during treatment was 1.6 kg (range, 0.1-5.7 kg). No patients experienced grade ≥3 treatment-related AEs. The study concluded that pencil-beam scanning IMPT was feasible and offered significant reductions in radiation exposure to multiple gastrointestinal organs at risk.
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