Initial Experience with Proton Beam Therapy for Differentiated Thyroid Cancer
This study reported outcomes of 14 patients with recurrent, radioactive iodine (RAI) refractory differentiated thyroid cancer (DTC) treated with IMPT. At 8 months, all patients were alive without local-regional failure.
Acute grade 3 toxicities were limited to 1 patient with dysphagia, requiring feeding tube placement. Two patients experienced late grade 3 esophageal stenosis requiring dilation. There were no grade 4 or 5 toxicities. The authors suggested that IMPT is a promising treatment for this patient population.