Intensity Modulated Proton Beam Therapy versus Volumetric Modulated Arc Therapy for Patients with Nasopharyngeal Cancer: A Propensity Score-Matched Study
This study conducted a retrospective propensity score matching analysis (1:1) of 80 NPC patients treated with IMPT and VMAT. At a median follow-up time of 24.1 months in the IMPT group, this study reported that PFS and OS were not statistically different between the two groups but potentially better in IMPT group.
The IMPT group had significantly less requirement for nasogastric (NG) tube placement and body weight loss during treatment due to the significantly lower mean dose of the oral cavity. However, IMPT increased the grade 3 radiation dermatitis.