Executive summary

This study conducted a retrospective propensity score matching analysis (1:1) of 80 NPC patients treated with IMPT and VMAT. At a median follow-up time of 24.1 months in the IMPT group, this study reported that PFS and OS were not statistically different between the two groups but potentially better in IMPT group.

The IMPT group had significantly less requirement for nasogastric (NG) tube placement and body weight loss during treatment due to the significantly lower mean dose of the oral cavity. However, IMPT increased the grade 3 radiation dermatitis.

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