Executive summary

This is a systematic review comparing the dosimetry parameters of proton free breathing (proton-FB) and/or proton with deep inspiration breath hold (proton-DIBH) to IMRT-DIBH. Based on the eight comparative studies included, this analysis found that for heart, lung, breast, and integral dose, proton therapy (FB or DIBH) was superior to IMRT-DIBH. Proton-DIBH can lower dose to the lungs and heart even further compared with proton-FB.

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