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Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis

08/07/2021
/ Publications
/
Chemotherapy
IMRT

This study retrospectively reviewed 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy. 25 patients (11.4%) underwent PBSPT...

Scanning Beam Proton Therapy (SPT) Versus Photon IMRT for Stage III Lung Cancer: Comparison of Dosimetry, Toxicity, and Outcomes.

05/03/2020
/ Publications
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IMRT

This study reviewed dosimetric data and clinical outcomes of 64 stage III lung cancer patients treated with SPT (34) + IMRT (30). Mean dose to lung, heart, and...

Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk.

10/10/2020
/ Publications
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IMRT
Secondary cancer

This study estimated secondary cancer risks for 23 mediastinal lymphoma patients treated with PBT in comparison with helical photon IMRT re-plans. PBT was...

Advanced radiation techniques for locally advanced NSCLC: IMRT and proton therapy.

08/08/2018
/ Publications
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IMPT
IMRT

This review article examined clinical outcomes data of IMRT and PBT for locally advanced NSCLC. This review pointed out that PBT is not considered the standard...

NTCP Models for Severe Radiation Induced Dermatitis After IMRT or PT for Thoracic Cancer Patients.

04/03/2020
/ Publications
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IMRT

In order to analyze the incidence of acute radiation induced dermatitis (RD) and develop normal tissue complication probability (NTCP) models for severe RD in...

High-dose Intensity-modulated proton therapy versus Standard-dose Intensity-modulated RadIation therapy for esophageal squamous cell carcinoma (HI-SIRI): study protocol for a randomized controlled clinical trial.

15/11/2022
/ Publications
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IMPT
IMRT

This is a study protocol details a randomized trial taking place in Thailand with multiple centers comparing IMPT and IMRT for stage II–IVA squamous thoracic...

Cardiopulmonary Toxicity Following Intensity-Modulated Proton Therapy (IMPT) Versus Intensity-Modulated Radiation Therapy (IMRT) for Stage III Non-Small Cell Lung Cancer.

15/11/2022
/ Publications
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IMPT
IMRT

163 consecutively treated patients with biopsy-proven, stage III NSCLC who received IMPT (n = 35, 21%) or IMRT (n = 128, 79%) were analyzed in this study...

Proton and photon radiotherapy in stage III NSCLC: Effects on hematological toxicity and adjuvant immune therapy.

28/03/2024
/ Publications
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IMPT
IMRT
Toxicity

This study reported the incidence of lymphopenia in 271 stage III NSCLC patients treated with IMPT (n=71) vs IMRT (n=200) and concurrent chemotherapy. The...

Single Institution Experience of Proton and Photon-based Postoperative Radiation Therapy for Non-small-cell Lung Cancer.

14/09/2021
/ Publications
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IMRT
Toxicity

This study retrospectively evaluated 136 postoperative radiotherapy (PORT) patients (61 PBT, 75 IMRT). Median OS was 76 and 46 months for PBT and IMRT with...

Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis.

14/07/2021
/ Publications
/
IMRT
Pencil Beam Scanning - PBS

For a cohort of 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy, 25 patients (11.4%) underwent PBSPT and 194 patients (88...